Result

Predicted Affinity Change (ΔΔGaffinity)

: -1.55 Kcal/mol (Reduced affinity)

      Mutation:

    • Wild-type residue: ARG
    • Position: 97
    • Mutant residue: ALA
    • Chain: H
    • Within Binding Interface: True
    • Distance: 3.13 Å

      Antibody Information:

    • Antibody formats: Fab
    • Antibody chains: H, L
    • Chothia annotation: H97(CDR-H3)
    • Your prediction has a HIGH confidence level.

Visualisation

PI
interactions
vdw
interaction
hydrogen
bond
ionic
bond
aromatic
bond
hydrophobic
bond
carbonyl
bond
polar
interaction








Sequence Viewer

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LIGHT CHAIN
HEAVY CHAIN

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